On 1 April 2021, local borough/county based Clinical Commissioning Groups merged to become single regional NHS Clinical Commissioning Groups (CCG) in line with NHS England’s Long Term Plan.

NHS Barking and Dagenham Clinical Commissioning Group, NHS City and Hackney CCG, NHS Havering CCG, NHS Newham CCG, NHS Redbridge CCG, NHS Tower Hamlets CCG and NHS Waltham Forest CCG have transferred to the new NHS North East London CCG

The respective Bedfordshire, Luton and Milton Keynes CCGs are now collectively known as Bedfordshire, Luton and Milton Keynes CCG.